Our Ethics Committee in July 2015 approved the protocol for the CCPP Research Biobank, a non-profit service unit aimed at the collection, processing, storage and distribution of human biological samples for scientific research purposes. This resource therefore addresses solidarity purposes, by making immediately available to researchers a number of biological samples and data, unimaginable until a few years ago.
As we strongly believe in the present and future importance of this great resource, the CCPP Biobank has joined the Italian BBMRI network (Biobanking and BioMolecular Resources Research Infrastructure of Italy) and is part of the National Node of the European Research Infrastructure of Biobanks and BioMolecular Resources (BBMRI-ERIC). It collects and stores biological samples and clinical data from subjects with various pathologies, such as neurodegenerative diseases including Parkinson’s and Alzheimer’s diseases and other pathologies such as Cerebral Stroke, Multiple Sclerosis and Peripheral Neuropathies. We also collect with special scientific interest biological samples from subjects with rare diseases, such as Amyotrophic Lateral Sclerosis (ALS), Primary Lateral Sclerosis (SLP) and Chronic Inflammatory Demyelinating Polyneuropathy (PCID).
In the CCPP Biobank, biological samples such as plasma, serum, peripheral blood mononuclear cells (PBMCs), DNA, whole blood and cerebro-spinal fluid (CSF), are recorded, pseudonymized through a dedicated software and then stored in very low-temperature freezers, in order to preserve their quality for a long time.
Subjects who consent to participate in the biobanking process, whether recruited as healthy or affected by pathologies, undergo an accurate clinical and cognitive assessment, thanks to an attentive evaluation by our multidisciplinary team consisting of Neurologists, Physiatrists, Pulmonologists, Geriatricians, Neuropsychologists, Physiotherapists, Occupational and Speech & Language Therapists.
According to the donors’ informed consent, CCPP Biobank samples and associated data are used in national and international scientific research projects carried out both within the CCPP lab of Neurobiology for Translational Medicine and in collaboration with other research centers. The aim is to contribute to the study of diseases and their underlying mechanisms, and to pursue the discovery of new biomarkers for early diagnosis and disease prediction and monitoring.
Data are processed in compliance with EU Regulation nr. 679/2016, in a protected and safe mode using encryption systems and access passwords to prevent access by whoever has not been formally authorized by the data processing Responsible person.
Donors can access the information from the research projects in which they were involved, and / or request the destruction of the biological sample, at any time.
The Director of the Biobank is Dr. Massimo Corbo.
The BioBank staff members are Pamela Cappelletti, PhD, and Melania Filareti, biologist.