The laboratory of neurobiology for translational medicine supports the clinic from a biochemical, genetic and molecular point of view, collecting as much data as possible from the same patient so as to better characterize it by adding the molecular aspect to the clinical picture.

The laboratory is equipped for biochemical analyzes (western blot, immunoprecipitations, protein expression, bioinformatics), immunohistochemistry (fluorescence, confocal), mass and genetic spectrometry (rtPCR, PCR, Sequencing)

Activities

The main activity concerns the analysis of human samples from blood samples of patients suffering from neurodegenerative diseases such as ALS, Alzheimer’s, Parkinson’s, on which are investigated the molecular, genetic and proteomic mechanisms that may vary both during the onset and the development of diseases.

Furthermore, it is also investigated how a rehabilitative path can create biomolecular modifications, thus trying to identify rehabilitative markers.

Furthermore, the laboratory is focused on the identification of new biomarkers for the early diagnosis of neurodegenerative diseases.

Team

Marco Feligioni, PhD (Pharmacologist) and director of the laboratory

Melania Filareti, biologist

Elena Ficulle, PhD student.